Ever noticed someone’s breathing getting deeper….. Then shallower…….. Then stopping completely for a few seconds…….and then starting all over again? Well, that’s not normal. That’s Cheyne-Stokes respiration. Well, it doesn’t sound familiar, but don’t worry. By the end of this blog, you will understand exactly what Cheyne-Stokes breathing is, why it happens, who’s at risk, how it connects to sleep apnea and heart failure. Most importantly, how can it be prevented?
Let’s break it down.
What is Cheyne-Stokes Respiration?
Cheyne-Stokes respiration (CSR) is an abnormal breathing pattern. Your breathing gradually gets deeper and faster, then it slowly becomes shallower and slower. It stops completely for a few seconds (this pause is called an apnea), then the cycle repeats. Each cycle typically lasts anywhere from 30 seconds to 2 minutes. The pause in breathing (apnea) usually lasts between 5 to 30 seconds. Most people with Cheyne-Stokes breathing don’t even realize it’s happening as it usually occurs during sleep.
The Cheyne-Stokes Breathing Pattern – What Does It Look Like?
Let’s visualize the Cheyne-Stokes breathing pattern step by step:
Phase 1: Hyperpnea (Deep, Fast Breathing) Breathing gradually becomes deeper and faster. The body is trying to get more oxygen.
Phase 2: Hypopnea (Shallow, Slow Breathing) Breathing gradually becomes shallower and slower. The body is now getting too much oxygen (and losing too much carbon dioxide).
Phase 3: Apnea (Breathing Stops) Breathing stops completely for a few seconds. No air moves in or out.
Phase 4: Cycle Repeats Breathing starts again – slowly at first, then deeper and faster. And the whole pattern repeats.
This isn’t just random. There’s a reason behind this pattern. And it has to do with how your brain controls breathing.
Cheyne-Stokes Respiration Causes – Why Does This Happen?
To understand Cheyne-Stokes respiration, you need to understand how breathing works. Your brain constantly monitors the levels of oxygen and carbon dioxide in your blood. When the carbon dioxide level drops, your brain tells you to slow down. In healthy people, this feedback system works smoothly.
But in people with certain health conditions, there is a delay in this feedback loop. The brain doesn’t get accurate signals in time. So it overcompensates, first by breathing too much, then by breathing too little, then by stopping altogether.
Also read: What Is a Healthy Sleep Cycle and Why Is It Important?
What causes this delay?
Several things. But the most common Cheyne-Stoke respiration causes include:
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Heart Failure (Especially Congestive Heart Failure)
This is the #1 cause. When the heart is weak, blood circulation slows down. This means the brain gets delayed information about blood oxygen and CO2 levels. The result? Cheyne-Stokes breathing. Studies show that Cheyne-Stokes respiration in congestive heart failure is extremely common – affecting up to 40-50% of heart failure patients.
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Stroke
A stroke damages the brain. And when the part of the brain that controls breathing is affected, Cheyne-Stokes respiration can develop.
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Brain Injuries or Tumors
Any damage to the brainstem or respiratory control centers can trigger this abnormal breathing pattern.
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High Altitude
At high altitudes, oxygen levels are lower. This can temporarily cause Cheyne-Stokes breathing even in healthy people.
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Kidney Failure
Kidney problems can affect blood chemistry, which in turn affects the brain’s breathing control signals.
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Drug-Induced (Opioids, Sedatives)
Certain medications can suppress the brain’s respiratory centers, leading to abnormal breathing patterns.
Cheyne-Stokes Breathing Seen In – Who’s at Risk?
Cheyne-Stokes breathing is seen in people with:
- Congestive heart failure (most common)
- Stroke
- Brain injuries
- Brain tumors
- Kidney failure
- End-stage organ failure
- People at high altitudes
- People on opioid medications
- Dying patients (end-of-life)
The connection between Cheyne-Stokes heart failure is particularly strong. If you or a loved one has heart failure and you notice unusual breathing patterns during sleep, it’s worth getting checked.
Also read: How to Stop Snoring: 16 Tips to Sleep Softly
What is the connection between central sleep Apnea and Cheyne-Stokes respiration?
You’ve probably heard of sleep apnea. But did you know there are different types?
- Obstructive Sleep Apnea (OSA): The airway gets physically blocked during sleep. This is the most common type.
- Central Sleep Apnea (CSA): The brain fails to send proper signals to the breathing muscles. The airway isn’t blocked – the brain just “forgets” to breathe.
Cheyne-Stokes respiration is a type of central sleep apnea.
In fact, when doctors diagnose central sleep apnea with Cheyne-Stokes respiration (CSA-CSR), they’re specifically looking for that crescendo-decrescendo breathing pattern we described earlier. So if you have central sleep apnea and Cheyne-Stokes respiration, it means your brain’s breathing control is disrupted, often due to heart failure or a neurological condition.
Cheyne-Stokes vs Other Abnormal Breathing Patterns
Cheyne-Stokes isn’t the only abnormal breathing pattern. Let’s compare it with others you might hear about:
| Feature | Cheyne-Stokes | Kussmaul |
| Pattern | Gradually increasing, then decreasing, with pauses | Deep, rapid, labored breathing – constant rate |
| Pauses | Yes (apnea periods) | No pauses |
| Cause | Heart failure, stroke, brain injury | Diabetic ketoacidosis, metabolic acidosis |
| Goal | Brain overcompensates for CO2 changes | The body is trying to blow off excess acid |
Kussmaul Respirations vs Cheyne-Stokes
| Feature | Cheyne-Stokes | Kussmaul |
| Pattern | Gradually increasing, then decreasing, with pauses | Deep, rapid, labored breathing – constant rate |
| Pauses | Yes (apnea periods) | No pauses |
| Cause | Heart failure, stroke, brain injury | Diabetic ketoacidosis, metabolic acidosis |
| Goal | The brain overcompensates for CO2 changes | The body is trying to blow off excess acid |
Key difference: Kussmaul respirations are deep and rapid but steady. Cheyne-Stokes has a waxing-waning pattern with breathing pauses.
Biot’s Respirations vs Cheyne-Stokes
| Feature | Cheyne-Stokes | Biot’s (Ataxic Breathing) |
| Pattern | Gradual increase/decrease (smooth wave) | Irregular, unpredictable breaths with sudden pauses |
| Rhythm | Regular cycling pattern | Completely irregular – no pattern |
| Cause | Heart failure, stroke | Severe brain damage, brainstem injury |
| Severity | Serious but treatable | Often indicates severe brain damage |
Key difference: Cheyne-Stokes has a predictable pattern. Biot’s respirations are chaotic and irregular.
Ataxic Respiration vs Cheyne-Stokes
Ataxic respiration is similar to Biot’s breathing – completely irregular with no predictable pattern.
| Feature | Cheyne-Stokes | Ataxic |
| Pattern | Predictable crescendo-decrescendo | Unpredictable, chaotic |
| Cause | Heart failure, neurological issues | Medulla (brainstem) damage |
| Prognosis | Treatable in many cases | Often, poor – indicates severe brain injury |
Key difference: Ataxic breathing usually indicates damage to the medulla (the brain’s breathing control center) and is often seen in life-threatening situations.
Also read: Excessive sleepiness – why do I feel sleepy all the time?
Cheyne-Stokes Respirations and Death – Is It a Sign of Dying?
Yes, Cheyne-Stokes breathing can be seen in dying patients. In end-of-life situations, as the body shuts down, the brain’s ability to regulate breathing deteriorates. This can lead to Cheyne-Stokes respirations.
However, this is important to note that Cheyne-Stokes breathing does NOT always mean someone is dying. Many people with heart failure or sleep apnea have Cheyne-Stokes respiration for years and live full lives with proper treatment.The context matters:
- In a heart failure patient being treated, Cheyne-Stokes is a manageable condition
- In an end-stage patient with multiple organ failure, it may be a sign that the body is shutting down
If you notice Cheyne-Stokes breathing in a loved one, don’t panic. Talk to their doctor to understand what it means in their specific situation.
Cheyne-Stokes Breathing Treatment – How Is It Managed?
Now for the good news. Cheyne-Stokes respiration treatment is available and effective in many cases. The treatment approach depends on the underlying cause.
1. Treating the Underlying Heart Failure
Since Cheyne-Stokes respiration heart failure is the most common cause, treating heart failure often improves the breathing pattern. This includes:
- Medications (diuretics, ACE inhibitors, beta-blockers)
- Lifestyle changes (diet, exercise, weight management)
- Cardiac rehabilitation
- In severe cases, devices like pacemakers or heart transplant
2. CPAP Therapy (Continuous Positive Airway Pressure)
CPAP delivers a steady stream of air pressure to keep the airways open and stabilize breathing.
While CPAP is most commonly used for obstructive sleep apnea, it can also help some patients with central sleep apnea and Cheyne-Stokes respiration.
3. ASV Therapy (Adaptive Servo-Ventilation)z
This is a more advanced form of therapy specifically designed for central sleep apnea and Cheyne-Stokes respiration. ASV machines are smart, they monitor your breathing pattern in real-time and adjust air pressure breath-by-breath to prevent apneas and stabilize breathing.
Note: ASV is not suitable for everyone. In some heart failure patients with very low ejection fraction, ASV may not be recommended. Always consult a sleep specialist.
4. Supplemental Oxygen
In some cases, providing extra oxygen during sleep can help reduce the severity of Cheyne-Stokes breathing.
5. Medications
Certain medications can help stimulate breathing:
- Acetazolamide: Helps reduce central apneas
- Theophylline: Stimulates the respiratory center
These are usually used in specific cases under medical supervision.
6. Treating Other Underlying Causes
If Cheyne-Stokes respiration is caused by stroke, kidney failure, or medication side effects, treating those underlying conditions can help resolve the breathing pattern.
Also read: The Link Between Gut Health and Sleep Quality
When Should You See a Sleep Doctor?
You must see a sleep specialist if you or a loved one experiences:
- Unusual breathing patterns during sleep (gasping, pausing, irregular breathing)
- Excessive daytime sleepiness
- Waking up frequently at night
- Shortness of breath, especially when lying down
- Known heart failure with new sleep problems
- Your partner notices that breathing stops during your sleep
Don’t ignore these signs. Early diagnosis and treatment can make a significant difference.
How RemeSleep Can Help?
At RemeSleep, we specialize in diagnosing and treating sleep-related breathing disorders, including central sleep apnea and Cheyne-Stokes respiration.
Our team of sleep specialists will:
- Conduct a comprehensive sleep study to identify your breathing pattern
- Determine the underlying cause of your sleep disorder
- Create a personalized treatment plan
- Provide ongoing monitoring and support
Whether you need CPAP therapy, ASV therapy, or a combination of treatments, we’re here to help you breathe easier and sleep better.
Don’t let abnormal breathing disrupt your sleep or your life.
Cheyne-Stokes respiration might sound intimidating. But now you know:
- What it is (an abnormal breathing pattern with crescendo-decrescendo cycles and pauses)
- Why it happens (delayed feedback in the brain’s breathing control, often due to heart failure)
- Who’s at risk (heart failure patients, stroke survivors, people with brain injuries)
- How it connects to sleep apnea (it’s a type of central sleep apnea)
- How it’s different from other patterns (Kussmaul, Biot’s, ataxic)
- How it can be treated (treating underlying causes, CPAP, ASV, oxygen, medications)
If you or someone you know is experiencing unusual breathing during sleep, especially with a history of heart failure, don’t wait.
Get evaluated. Get treated. Get better sleep.
